September 25th
07:00 – Open for Industry
08:00 – Registration
09:00 – Welcome
Jan Buer, Tobias Tertel, Bernd Giebel, Kerstin Menck
09:15 – Session 1: EV Biogenesis, Cargo & Function
Chairs: Tobias Tertel (Essen), Kerstin Menck (Münster)
09:15 – Elke Pogge-von Strandmann
Decoding EV Communication: Cargo or Surface Signals in Tumor Biology
Zentrum für Tumor- und Immunbiologie, Philipps-Universität Marburg
09:45 – Karen Lahme
Podocyte exopher-like vesicle formation in membranous nephropathy
Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
10:00 – Ivanka Saßmannshausen
The Adapter Protein CD2AP is a novel Regulator of the Biogenesis of Syntenin Exosomes
Dept. of Medicine A, Haematology, Oncology, and Pneumology, University of Münster, Münster, Germany
10:15 – Daniel Rey
Determining tetraspanin positivity and quantifying surface protein of EV’s using the NanoAnalyzer
NanoFCM
10:25 – Poster talks
10:45 – Coffee Break ☕
11:15 – Session 2: EV Characterization & Standardization
Chairs: Michael Pfaffl (München), Tanja Kutzner (Essen)
11:15 – Tobias Tertel / Christian Preußer
Mind the Steps: Pre-analytical Factors and Methodological Choices in EV Analysis
Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; EV-iTEC, Center for Tumor Biology and Immunology, Philipps University Marburg
11:45 – Maria Anthi Kakavoulia
In-Solution Characterization of Extracellular Vesicles by Flow Induced Dispersion Analysis (FIDA): A Novel Approach to Antibody Binding and Surface Interaction Analysis
Biochemistry and Chemistry, Department of Veterinary Science, Ludwig-Maximilians-Universität Munich, Lena-Christ-Str.48, 82152 Planegg
12:00 – Isabel Graf
High Purity Fluorescence-Activated Vesicle Sorting for Enrichment of Specific Extracellular Vesicle Populations
Laboratory for Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
12:15 – Matthias Hackl
Small RNA-sequencing (miND®) Enables Discovery of EV-specific MicroRNA Signatures to Support EV Therapeutics Development
TAmiRNA
12:25 – Poster talks
12:45 – Lunch with Posters I 🍽️
14:30 – Session 3: Reproducibility, Pitfalls, and Open Questions in EV Research
Moderator: Eva-Maria Albers (Mainz), Bernd Giebel (Essen)
14:30 – Rienk Nieuwland
Same sample, different day. Reproducibility of EV research
University of Amsterdam · Chair, Amsterdam Vesicle Center (AVC)
15:00 – Roundtable discussion
16:00 – Coffee Break ☕
16:30 – Session 4: EVs in Neurological & Cardiovascular Diseases
Chairs: Yiqiao Zhang (Essen), Christian Preußer (Marburg)
16:30 – Josephine Herz
TBA
Department of Paediatrics I, University Hospital Essen, University of Duisburg-Essen
17:00 – Katharina Helena Morawitz
Extracellular Vesicles in Plasma and Lipoaspirates of Lipedema Patients and Healthy Control Individuals
HMU Health and Medical University Potsdam, Potsdam, Germany
17:15 – Xinyue Zhou
Brain Metastasis-derived sEVs Induce Neutrophil-Mediated Immune Suppression
Department of Dermatology and Allergy, LMU Hospital, Ludwig-Maximilians-University, Munich, Germany
17:30 – Zoey Wang
EXODUS, A High Efficiency System for Automated EVs Isolation
Exodus Bio
17:40 – Poster talks
19:30 – Dinner and get together 🍷
September 26th
09:00 – Session 5: EVs in Immune Regulation & Inflammation
Chairs: Julia Groß (Potsdam), Venkatesh Kumar Chetty (Essen)
09:00 – Carlos Salomon Gallo
Translational Opportunities for Extracellular Vesicle Biomarkers: A Case Study in Ovarian Cancer
UQ Centre for Extracellular Vesicle Nanomedicine, The University of Queensland
09:30 – Mohamed Elbeltagy
CD39-Engineered Mesenchymal Stromal Cell-Derived Extracellular Vesicles Enhance Immunomodulation and Neuroprotection in Ischemic Stroke via Anti-Inflammatory Adenosine
Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
09:45 – Jamal Ghanam
Small Extracellular Vesicle Release Blockade Activates cGAS Pathway and Increases NK Cytotoxicity through ULBP1 Activation
Clinic for General, Visceral, Vascular and Transplant Surgery, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany
10:00 – Christina Klasen
ZetaView® Evolution – Your EV solution
Particle Metrix
10:10 – Poster talks
10:30 – Coffee Break ☕
11:00 – Session 6: EVs in Cross-Kingdom Communication
Chairs: Janis Müller (Marburg), Basant Thakur (Essen)
11:00 – Amy Buck
Vesicular and non-vesicular RNA transmission in animals: lessons from parasites
Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh
11:30 – Saman Ghodsi
Extracellular vesicles and whole-body regeneration in planarian Schmidtea mediterranea: Hints for a conserved role
Pluripotency and Regeneration Group, Department of Animal Physiology, University of Osnabrück, Osnabrück, Germany
11:45 – Cláudia Vilhena
The role of pneumococcal extracellular vesicles on the pathophysiology of the kidney disease hemolytic uremic syndrome
Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany
12:00 – Toni Weinhage
Flow Cytometry Solutions for Extracellular Vesicle Research
Beckman Coulter
12:10 – Poster talk
12:30 – Lunch with Posters II 🍽️
14:15 – Session 7: EVs in Cancer
Chairs: Jamal Ghanam (Essen), Claudia Günther (Erlangen)
14:15 – Héctor Peinado
Beyond the premetastatic niche: EV-inspired strategies to boost immunotherapy
Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain
14:45 – Marcel Kemper
Immune Cell-Derived Large Extracellular Vesicles as Biomarkers of Immunotherapy Efficacy in NSCLC
University of Münster, Dept. of Medicine A, Hematology, Oncology and Pneumology, Münster, Germany
15:00 – Rambod Nikbakhsh
P53-dependent Effects of Tumor-derived Extracellular Vesicles on the Formation of Lung Metastasis
Institute for Tumor Immunology, Center for Tumor Biology and Immunology (ZTI), Philipps University Marburg, Marburg, Germany
15:15 – Tarik Hadi
Maximizing MSC-EV Yield with Preserved Quality Using a Xeno-Free, Defined Formulation
Takara
15:25 – Poster talks
16:00 – Closing Ceremony and prizes
16:30 – End