See the program details here!
Thursday, March 6, 2025
GSEV-1: EV Biology: From membrane architecture to cellular responses
⏰ 09:00–10:30
Chairs: Kerstin Menck (Münster), Christian Preußer (Marburg)
- Welcome – Kerstin Menck (Münster)
- The role of EV fusion with target cells in triggering systemic inflammation – Heiko Herwald (Lund)
- Protein targeting to exosomes and EV docking at target neurons – Matthias Kneussel (Hamburg)
- Remodelling of bilayer membranes and nanovesicles – Reinhard Lipowsky (Potsdam)
- Multidrug resistance transporter Abcg2 activity maintains stem cell quiescence by extracellular vesicle-mediated extract – Stefan Momma (Frankfurt)
GSEV-2: News in technologies and standardization
⏰ 14:00–15:30
Chairs: Tobias Tertel (Essen), Andre Görgens (Huddinge)
- Single particle profiler for measuring content and properties of bioparticles at the nanoscale – Erdinc Sezgin (Stockholm)
- From variability to reproducibility: standardizing extracellular vesicle flow cytometry – Britta Bettin (Amsterdam)
- Exploring the role of extracellular vesicles in glioblastoma pathophysiology and biomarker discovery – Franz Ricklef (Hamburg)
- Single-cell analyses of EV recipients: Tellurium-based labeling of the EV proteome (TeLEV) and beyond – Daniel Bachurski (Köln)
GSEV-3/GSCN-1: EV Therapy
⏰ 16:00–17:30
Chairs: Bernd Giebel (Essen), Daniel Besser (Berlin)
- Scaling up production of extracellular vesicles for treatment of Parkinson’s disease – Augustas Pivoriunas (Vilnius)
- Human Cell-derived EVs as Drug Candidates – How to Address Regulatory Standards – Eva Rohde (Salzburg)
- Mesenchymal Stromal Cells: EVs or not EVs? – Karen Bieback (Mannheim)
- Mission impossible? Translation of EVs into the clinics – A roundtable discussion
Friday, March 7, 2025
GSEV-4: EVs in cancer
⏰ 09:00–10:30
Chairs: María Gómez-Serrano (Marburg), Daniel Bachurski (Köln)
- EVs promote an immunosuppressive and tumor-supportive microenvironment in chronic lymphocytic leukemia – Jérôme Paggetti (Luxembourg)
- Immunomodulatory functions of EVs in the tumor microenvironment – Viviane Ponath (Marburg)
- Lipidomic profiling of extracellular vesicles – a potential alternative to tumour biopsy – Zoltan Takats (Regensburg)
- Targeting EMT – Unlocking the potential of extracellular vesicle pathway inhibition in aggressive brain tumors – Kendra Maass (Heidelberg)
GSEV-5: EVs in neuroscience
⏰ 11:00–12:30
Chairs: Kendra Maass (Heidelberg), Eva-Maria Krämer-Albers (Mainz)
- Central nervous system-derived extracellular vesicles: the next generation of neural circulating biomarkers? – David Otaegui (San Sebastián)
- Complexity of the blood-brain barrier and what this means for EVs – Stefan Liebner (Frankfurt)
- Extracellular Vesicles in Stroke: Pathways to Neuroprotection and Repair – Berta Puig Martorell (Hamburg)
- Cellular Crosstalk in Brain Development and Neurodevelopmental Disorders – Silvia Cappello (München)
GSEV-7/IGLD-12: Clinical Diagnostics
⏰ 16:00–17:30
Chairs: Michael Pfaffl (Freising), Stefan Holdenrieder (München)
- Plasma and Saliva EVs as promising liquid biomarkers in head and neck cancer – Marie-Nicole Theodoraki (München)
- Large extracellular vesicles as novel predictive biomarkers for immunotherapy in non-small cell lung cancer – Kerstin Menck (Münster)
- cfRNA Biomarker Signatures for Liquid Biopsy Monitoring in Anaplastic Thyroid Cancer Cells – Christian Grätz (München)
- A decade of extracellular vesicle-associated DNA: potential and challenges as biomarkers in cancer – Basant Thakur (Essen)
💻 For further information and to register, visit: IGLD Program and Registration
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