GSEV Program Highlights at IGLD2025

See the program details here!

Thursday, March 6, 2025

GSEV-1: EV Biology: From membrane architecture to cellular responses

⏰ 09:00–10:30
Chairs: Kerstin Menck (Münster), Christian Preußer (Marburg)

  • Welcome – Kerstin Menck (Münster)
  • The role of EV fusion with target cells in triggering systemic inflammation – Heiko Herwald (Lund)
  • Protein targeting to exosomes and EV docking at target neurons – Matthias Kneussel (Hamburg)
  • Remodelling of bilayer membranes and nanovesicles – Reinhard Lipowsky (Potsdam)
  • Multidrug resistance transporter Abcg2 activity maintains stem cell quiescence by extracellular vesicle-mediated extract – Stefan Momma (Frankfurt)

GSEV-2: News in technologies and standardization

⏰ 14:00–15:30
Chairs: Tobias Tertel (Essen), Andre Görgens (Huddinge)

  • Single particle profiler for measuring content and properties of bioparticles at the nanoscale – Erdinc Sezgin (Stockholm)
  • From variability to reproducibility: standardizing extracellular vesicle flow cytometry – Britta Bettin (Amsterdam)
  • Exploring the role of extracellular vesicles in glioblastoma pathophysiology and biomarker discovery – Franz Ricklef (Hamburg)
  • Single-cell analyses of EV recipients: Tellurium-based labeling of the EV proteome (TeLEV) and beyond – Daniel Bachurski (Köln)

GSEV-3/GSCN-1: EV Therapy

⏰ 16:00–17:30
Chairs: Bernd Giebel (Essen), Daniel Besser (Berlin)

  • Scaling up production of extracellular vesicles for treatment of Parkinson’s disease – Augustas Pivoriunas (Vilnius)
  • Human Cell-derived EVs as Drug Candidates – How to Address Regulatory Standards – Eva Rohde (Salzburg)
  • Mesenchymal Stromal Cells: EVs or not EVs? – Karen Bieback (Mannheim)
  • Mission impossible? Translation of EVs into the clinics – A roundtable discussion

Friday, March 7, 2025

GSEV-4: EVs in cancer

⏰ 09:00–10:30
Chairs: María Gómez-Serrano (Marburg), Daniel Bachurski (Köln)

  • EVs promote an immunosuppressive and tumor-supportive microenvironment in chronic lymphocytic leukemia – Jérôme Paggetti (Luxembourg)
  • Immunomodulatory functions of EVs in the tumor microenvironment – Viviane Ponath (Marburg)
  • Lipidomic profiling of extracellular vesicles – a potential alternative to tumour biopsy – Zoltan Takats (Regensburg)
  • Targeting EMT – Unlocking the potential of extracellular vesicle pathway inhibition in aggressive brain tumors – Kendra Maass (Heidelberg)

GSEV-5: EVs in neuroscience

⏰ 11:00–12:30
Chairs: Kendra Maass (Heidelberg), Eva-Maria Krämer-Albers (Mainz)

  • Central nervous system-derived extracellular vesicles: the next generation of neural circulating biomarkers? – David Otaegui (San Sebastián)
  • Complexity of the blood-brain barrier and what this means for EVs – Stefan Liebner (Frankfurt)
  • Extracellular Vesicles in Stroke: Pathways to Neuroprotection and Repair – Berta Puig Martorell (Hamburg)
  • Cellular Crosstalk in Brain Development and Neurodevelopmental Disorders – Silvia Cappello (München)

GSEV-7/IGLD-12: Clinical Diagnostics

⏰ 16:00–17:30
Chairs: Michael Pfaffl (Freising), Stefan Holdenrieder (München)

  • Plasma and Saliva EVs as promising liquid biomarkers in head and neck cancer – Marie-Nicole Theodoraki (München)
  • Large extracellular vesicles as novel predictive biomarkers for immunotherapy in non-small cell lung cancer – Kerstin Menck (Münster)
  • cfRNA Biomarker Signatures for Liquid Biopsy Monitoring in Anaplastic Thyroid Cancer Cells – Christian Grätz (München)
  • A decade of extracellular vesicle-associated DNA: potential and challenges as biomarkers in cancer – Basant Thakur (Essen)

💻 For further information and to register, visit: IGLD Program and Registration

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